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Thursday, May 15, 2014

Zebrafish larvae (Danio rerio) activity monitoring.

The new HVS Image 2014 also contains the most cost effective Zebrafish larvae activity monitoring system ever. Using a standard camera the system is IR sensitive and by using ANSI and SBS compliant IR-translucent multi-well plates and setting the software to either 96 fields or 48 fields simultaneously you can have an inexpensive, efficient system for high throughput tracking of zebrafish larvae (Danio rerio). Details at HVSImage


Wednesday, May 14, 2014

New data formats allow more flexible analysis for open field.

The Open Field modules of HVS Image 2014.4 [1] (Beryllium build) now offer an additional open file format, BOND (Behavioral OpeN Data files) for storing digital data, which can be used and implemented by anyone. These can can be implemented by both proprietary and free and open source software, using the typical software licenses used by each. In contrast to closed formats,  open formats (also called free file formats) are not encumbered by any copyrights, patents, trademarks or other restrictions (for example, if they are in the public domain) so that anyone may use it at no monetary cost for any desired purpose. The basic BOND format is based on the JSON standard outlined here http://www.ecma-international.org/publications/files/ECMA-ST/ECMA-404.pdf 

Monday, May 12, 2014

The new Noah - tracking the animals in open field 2 x 2 - and now 3 x 3

It's always been useful to get more data from a single open-field video set up by tracking the animals in open filed 2 x 2 - and now HVS Image 2014 can track 9 or more animals by setting up the cages 3x3 (or even 4x4 or 5x5 if you like) Find out more at hvsimage.com

Saturday, November 2, 2013

Open Field Workshop Announcement

HVS Image are presenting an Open Field Workshop at SFN 2013. Anyone can attend - just visit booth 335. See their announcement below:

Society for Neuroscience 2013

Timetable for Scientists interested in Morris Water Maze, T Maze, Y Maze, Elevated Plus Maze, Barnes Maze, Radial Arm Maze, Open Field, Novel Object Recognition, VNST Virtual Navigation on a Spherical Treadmill, Human Virtual Maze, Dry Analogs of Water Maze and Custom Protocols

Saturday, 9 November, 2013:
16:30 Toast some marshmallows on the open flames see the sunset over the Pacific. Network and chat with other behavioral neuroscientists and meet HVS Award Winners at the 4th floor Pool Bar & Grill MANCHESTER GRAND HYATT SAN DIEGO, One Market Place, San Diego, California, USA, 92101

Sunday, 10 November,2013:
11:00 Milk & Cookies! 11am every day drop by and join us for free milk (and soft drinks) and freshly baked cookies from "Uncle Biff's Killer Cookies" San Diego's tastiest cookies.  "They really do make the perfect chocolate chip cookie." Free milk too. Make sure you come in time - they'll go fast! At booth 335.
11:15 HVS Image 2013 Special Presentation:  Dr Jhodie Duncan, Florey Institute of Neuroscience and Mental Health, Department Anatomy & Neuroscience: At booth 335.
Chronic Intermittent Toluene Inhalation During Adolescence Alters Reinforcement Learning & Causes Long-Term Glutamatergic Dysfunction.

11:40 HVS Image 2013 Special Presentation:  Matthew R Holahan, PhD., Department of Neuroscience, Carleton University: At booth 335.
Connectivity-based changes during a late, postnatal developmental period in the hippocampus

16:00 HVS Image regalia give away. T-Shirts, Mugs, Pens, hats.  At booth 335.
21:00 Free Drink and Scientist Meetup at top San Diego Nightclub - The Altitude Sky Lounge  (tickets only - pick a ticket up from us any time at booth 335)
Monday, 11 November,2013:
11:00 Milk & Cookies! 11am every day drop by and join us for free milk (and soft drinks) and freshly baked cookies from "Uncle Biff's Killer Cookies" San Diego's tastiest cookies.  "They really do make the perfect chocolate chip cookie." Free milk too. Make sure you come in time - they'll go fast!  At booth 335.
11:15 HVS Image 2013 Special Presentation:  Áine Mary Duffy, Ph.D., Center for Dementia Research, The Nathan Kline Institute for Psychiatric Research:  At booth 335.
Thioflavin-S staining and an antibody to amyloid-β (Aβ), 6E10, were used to examine Aβ-plaque. 
11:40 HVS Image 2013 Special Presentation:  Bechara Saab, PhD, Brain Research Institute, University of Zurich:  At booth 335.
Studying the platform-relocation version of the water maze. A method paper on the technique which discusses the theoretical and practical implications of the paradigm.

16:00 HVS Image regalia give away. T-Shirts, Mugs, Pens, hats. At booth 335.

Tuesday, 12 November, 2013
11:00 Milk & Cookies!. 11am every day drop by and join us for free milk (and soft drinks) and freshly baked cookies from "Uncle Biff's Killer Cookies" San Diego's tastiest cookies.  "They really do make the perfect chocolate chip cookie." Free milk too. Make sure you come in time - they'll go fast!  At booth 335.
11:15 HVS Image 2013 Special Presentation: Nokuthula Makena, Department of Human Biology, University of Cape Town:
Elevated plasticity-related protein levels post-exercise do not predict the outcome of spatial learning and memory in the Morris Water Maze task in maternally separated rats. At booth 335.

14:00 The Special Behavioral Techniques Workshop:

  • Morris Water Maze (Dr Jhodie Duncan PhD)
  • Open Field (Dr Bechara Saab PhD)
  • Plus Maze (Dr Matthew Holahan PhD)
  • Novel Object Recognition/placement (Dr Áine Duffy PhD)
16:00  HVS Image regalia give away. T-Shirts, Mugs, Pens, hats.

Wednesday, 13: November,2013:
11:00 Milk & Cookies! 11am every day drop by and join us for free milk (and soft drinks) and freshly baked cookies from "Uncle Biff's Killer Cookies" San Diego's tastiest cookies.  "They really do make the perfect chocolate chip cookie." Free milk too. Make sure you come in time - they'll go fast!  At booth 335.
12:00 $250 iTunes and Amazon card give-aways. If you might be interested in ordering HVS Image Software soon drop in to booth 335 and get a voucher that will give you your choice of a $250 iTunes and Amazon card when you order. At booth 335.
If you are interested in Morris Water Maze, T Maze, Y Maze, Elevated Plus Maze, Barnes Maze, Radial Arm Maze, Open Field, Novel Object Recognition, VNST Virtual Navigation on a Spherical Treadmill, Human Virtual Maze, Dry Analogs of Water Maze or Custom Protocols come to booth 335 at any time to chill out on our sofas, get your cell phone charged or to tell us about your tracking and analysis needs.
HVSImage Software Ltd.
Copyright HVS Image Software Ltd © 2013 http://www.hvsimage.com 

Monday, July 1, 2013

Craft, Above All

Visiting labs I keep on coming across 25 year old HVS Image VP112s still working perfectly and typically now outlasting their original owners and PIs, although now it is nearly impossible to find a personal computer that will link to the old RS232 interface far more run the old MS-DOS 3.1 software.

Thinking about the old VP112s reminds me of Walter Isaacson's comments on Steve Jobs's design philosophy. Under Jobs, Apple became famous for a level of craft that seemed almost gratuitous: For example, on the "Sunflower" Macintosh of a few years ago, there was an exquisitely fine, laser-etched Apple logo. As an owner, you might see that logo only once a year, when moving the computer. But it mattered, because that single time made an impression. 

If you remember the old VP110s, VP112s and VP118s you'll remember that HVS Image followed the seminal phrase coined by architect Louis Sullivan's - that "form ever follows function. This is the law." So there are no engraved Sunflowers but if you ever look inside and HVS Image VP - as I looked inside some of the earliest HVS Image trackers in the 1970s and architecture which was not just clean and orderly but was organised to perfection - every wire every, circuit board, every component in its place. PIs may not have see the deep beauty of the VP112 (although they appreciated the elegant simplicity of the interface), but many a technician did and any that where around at that time would not be surprised to see them working now without a glitch. 

Just like Steve Jobs this level of craft was one of the first design lessons that I ever got, and like Jobs this was learned at the hands of my father. 

My childhood home was lined with robot components (early machine vision system, robot arms as well as autonomous vehicles) and physics texts rather than fences and cabinets, but still - the lesson was learned and the philosophy continues in HVS Products.

Friday, June 21, 2013

Analysis techniques for Dry Mazes, Morris Water Maze and the Open Field Test

Characterization and Quantification of Spatial Learning Strategies.

These really fall into the category of sharing ones own notebook with the online community and I'm afraid without scaffolding - but I still welcome informed feedback. We've been looking at an additional "derivative" class of analysis parameters that might be shared over multiple assays. These include turning latency, decision frequency and decisional entropy.  There is a considerable similarity between some of my previous predictive behavior work and OFT/MWM etc in that the concept of choice modeling as a temporal Markov chain occurs in both.  Looking at the way things are modelled, measuring the first differential of the data refocuses the assay in the subjects decision making process and search strategies and moves the analysis to an animal centred approach from what is otherwise a meta analytical approach.

Monday, June 17, 2013

Open Field Test Analysis

Here are the new screenshots of the HVS Image Open Field Test Analysis module in HVS Image 2013. Its set to a 5x5 grid but actually grid sizes can be anything from 2x2 to 255x255. As always you can define HVS Custom files but now you you choose the special areas in the Open Field Test Analysis by pointing and clicking on them. Multiple files are selected by clicking and multi-selecting the source data files.

Open Field Test Analysis